TIA! Look up senomyx. (, It is common that sometimes consumers have health concerns whether PGPR is bad for our health and what are the side effects. Amazon.com. That doesnt necessarily quell concerns, however. I recently ate a Cadburys milk chocolate bar and decided to check the ingredient list after I noticed it didnt taste as good as it usually does. Because household cleaners often contain propylene glycol, I encourage you to try my. "[10] Additionally, no evidence was found of interference with normal fat metabolism, nor with growth, reproduction, and maintenance of tissue. What kinds of food packaging have you found this ingredient in? Polyglycerols preparation: Glycerol is heated to above 200 in the presence of an alkali catalyst to produce polyglycerol. Many people are extremely concerned by the presence of an ingredient in antifreeze (one thats used to deice airplanes, no less) in their food, which has sparked uproar in recent years, especially when three European countries pulled a popular alcoholic drink off the shelves for an illegal level of propylene glycol. Language links are at the top of the page across from the title. U.S. Food and Drug Administration. A keyword search in the Web of Science found 313 articles describing biostimulants containing PGPR published since 1998 ('biostimulant' AND ('rhizobacteria' OR . Before the completed growth of these enzyme pathways, parents should avoid allowing their children to ingest or be exposed to many chemicals that are potentially harmful, and pregnant mothers should do the same. As we wrote in a similar Wolfe debunker about the dangers of Pop Tarts, however, while the long-term health effects in humans exposed to high or chronic doses of TBQH (i.e. J Basic Microbiol. Ricinoleic acid: It is safe as an edible fats and oils and it was not of toxicological concern nor possible allergenicity. Production | Uses | Safety | Side effects | Conclusion. Several substances produced by antagonistic rhizobacteria have been related to pathogen control and indirect promotion of growth in many plants, such as siderophores and antibiotics. The https:// ensures that you are connecting to the Rejuvenates and regenerates tissue. Unauthorized use of these marks is strictly prohibited. After discontinuing the drug that poisoned her body, her condition stabilized for a period of time, but she later died after her condition deteriorated again. Ignoring the fact that the same could be said about the ingredients in the natural version of peanut butter cups presentedbelow Wolfe'sarticle,it is also a broad misrepresentation of PGPRs risk, which is, at best, negligible. Note that the numbers in parentheses (1, 2, etc.) There have, in fact, been animal studies that report harmful effects after extremely large doses of TBHQ as well as other cases of extremely high or chronic exposure resulting in harm. (11), The one area in which the CDCs toxicity profile negatively assessed propylene glycol was in the area of neurological symptoms. As you can learn that PGPR is made from the synthesis, thats why it is not natural. ( 6) If exposed to the eyes and facial area, propylene glycol can also be an irritant and cause mild conjunctivitis. Polyglycerol polyricinoleate (PGPR), E476, is an emulsifier made from glycerol and fatty acids (usually from castor bean, but also from soybean oil). Hersheys you better listen to your consumers. This post, though essentially a word-for-word rip-off of a 2015 post from a website named Living Traditionally, is still somehow classic Wolfe: a highly shareable story crafted at the expense of a beloved childhood candy through the willful misrepresentation of the science surrounding its ingredients. Food Chem Toxicol. The most recent review of its safety, performed by the European Food Safety Authority (EFSA) and adopted on 3 March 2017, reaffirmed its safety: PGPR [] is not of concern with regard to genotoxicity or carcinogenicity. They enhance crop growth and can help in sustainability of safe environment and crop productivity. . Plant growth-promoting bacteria can promote plant growth and use their own metabolism to solubilize phosphates, produce hormones and fix nitrogen, and they can directly affect plant metabolism. i eat those instead. Just like PGPR. 1998 Sep-Oct;36(9-10):719-38. doi: 10.1016/s0278-6915(98)00055-6. Children who are exposed to this chemical may show anxiety, restlessness, and increased ADHD symptoms. (. PGPR are highly diverse and in this review we focus on rhizobacteria as biocontrol agents. The Panel on Food Additives and Nutrient Sources added to Food (ANS) provides a scientific opinion re-evaluating the safety of polyglycerol polyricinoleate (PGPR, E 476) used as a food additive. Propylene glycol (often referred to as PG) is the third product in a chemical process beginning with propene, a byproduct of fossil fuel (oil refining and natural gas processing) and also found in nature as a byproduct of fermentation. It can also. Also you may be clear with some common FAQs such as is it gluten free and vegan. . Using an over 30 year old study of pregnant and developing rats fed absurdly unrealistic doses of a chemical to say that peanut butter cups are dangerous is a reach, even by Wolfe standards. industrial or laboratory workers handing pure TBHQ occupationally) is not a settled issue, the long-term effects of humans exposed to it in doses legally allowed by USA and European regulatory agencies is settled. However, bags with BB date 11 2022 and 03 2022 do have PGPR. (, One interesting case study followed a 24-year-old woman diagnosed with pneumonia. This isnt just limited to makeup. PGPR also help release small bubbles generated during the moulding process, thereby avoiding bubbles and holes in the chocolate product. I recently bought a 6 pack of Hersheys chocolate bars and I did not notice any change in taste or texture. When taken by mouth: Lecithin is commonly consumed in foods. Because household cleaners often contain propylene glycol, I encourage you to try my Homemade House Cleaner recipe. It is common that sometimes consumers have health concerns whether PGPR is bad for our health and what are the side effects. and symptoms have been commonly associated with propylene glycol exposure, mostly in part due to a few case studies that have caused alarming concern. Thank you for your article and insight. Ate Hershey with almonds and I had allergic reaction It is strong lipophilic W/O emulsifier and can form stable emulsions even when the water content is very high. National Library of Medicine It is a type of polyglycerol esters (PGE) with the European food additive number E476. 2. (Plus Top Benefits and Uses for Skin), Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More, Top 8 Healthy Cooking Oils (Plus, the Ones to Avoid Entirely), Is Corn Oil Healthy? A great number of cosmetics include propylene glycol, but in the U.S., Frozen desserts (ice cream, frozen yogurt, etc. Too many people have cancers, allergies and debilitating autoimmune diseases. MeSH See this image and copyright information in PMC. I had a violent allergic reaction with a very itchy rash that lasted for a week. What is Monosodium Glutamate (MSG E621) in food: Is it Bad for you? While the mechanisms linking soy to any hormone-derived maladies have yet to be demonstrated, it is another moot point, as at most only trace amounts of soy protein, if any, remain in soy lecithin. Found in Hershey kiss birthday cake flavor.was looking for whatever the bitter aftertaste is fromprob all that artificial coloringgrandkids requested cookies w thesemade cookies from scratchthen topped w poison. Overall, it did not "constitute a human health hazard". Has few side effects. HHS Vulnerability Disclosure, Help Fat balance tests confirmed that digestion and absorption of PGPR took place. It tasted nasty so I checked the ingredients list and saw PGPR listed, which I think is probably a recent addition. List a customer. I dont understand why you are changing the way chocolate is made. Let me know in the comments. efficiently and should avoid exposure when possible. The present study was aimed to investigate the effects of plant growth promoting rhizobacteria (PGPR) and plant growth regulators (PGRs) on the physiology and yield of wheat grown in less fertile sandy soil. [2] PGPR can also be used to reduce the quantity of cocoa butter needed in chocolate formulations: the solid particles in chocolate are suspended in the cocoa butter, and by reducing the viscosity of the chocolate, less cocoa butter is required,[2] which saves costs, because cocoa butter is an expensive ingredient, and also leads to a lower-fat product. As its a fairly common ingredient in smoke machines (for theater productions) and other inhalable substances, this is an important distinction to make. PGPR is a mixture of esterified products manufactured by the esterification of polyglycerol with condensed castor oil fatty acids. Found it in York Peppermint patty, Ive never seen it before and decided to look it up. Induced systemic resistance (ISR) in plants: mechanism of action. When I find PGPR in chocolate, I discontinue purchase. TBHQ, used as an antioxidant preservative in many food items, is indeed a petroleum derivative (as are almost all carbon containing compounds not produced by living organisms), but that doesnt mean it carries the same risks as ingesting raw petroleum sludge its a specific, singular, isolated, and modified chemical. Children who are exposed to this chemical may show anxiety, restlessness and intensified ADHD symptoms. I dont eat soy in any other food items either. Too many people have cancers, allergies and debilitating autoimmune diseases.. Bent E. Induced systemic resistance mediated by plant growth-promoting rhizobacteria (PGPR) and fungi (PGPF) In: Tuzun S, Bent E, editors. (14). A food additive claimed natural usually meet two requirements: 1) can be found in natural 2) made from extraction or fermentation or other manufacturing process that can be called natural instead of chemical synthesis. Soybean Isoflavone Exposure Does Not Have Feminizing Effects on Men: A Critical Examination of the Clinical Evidence." A Cadbury product, Fruit and Nut bar, also lists in the ingredients. Beneficial phytomicrobiome members, including plant growth promotion rhizobacteria (PGPR), enhance plant growth by improving nutrient absorption, producing phytohormones, and releasing antibiotics to manage biotic stress ( Lyu et al., 2020; Sindhu et al., 2020 ). I would like to help readers expand their knowledge of ingredients in their food. The consumption of PGPR by humans produced no adverse effects. PMC Never noticed this ingredient until recently. Heart disease and symptoms have been commonly associated with propylene glycol exposure, mostly in part due to a few case studies that have caused alarming concern. After reading what PGPR is and what it does, it occurred to me Hersheys must be putting this in their chocolate to be able to make the bars thinner saving the company money because the price of cocoa has gone up and this is a way to use less cocoa. In recent years, there has been much frustration and confusion about the chemical compound known as propylene glycol. Im down to eating Ghirardelli baking chocolate now. I recently discovered it in most Hershey products as some have commented above and, like Lynn, decided to look it up. I have a compromised immune system and this could have been so much worse. Resistance-inducing and antagonistic rhizobacteria might be useful in formulating new inoculants with combinations of different mechanisms of action, leading to a more efficient use for biocontrol strategies to improve cropping systems. Keywords: Excellent article and comments, thanks! (13) Again, this is an example of the rare (but possible) effects of the accumulation of propylene glycol in your system. No, a study published in Food Chem Toxicol in 1998 demonstrated that no carcinogenic effect of PGPR was observed. Itrates, a 3 on itshealth concerns scale, meaning the hazard it presents is moderately low. Nothing is safe just because FDA &/or WHO (Bill Gates) claim it is. All about Gelatin: Sources, Types, Made of, Production, Uses and More. How does it react with physiology of the body? 14.2.1 Role of PGPR as a Plant Growth Enhancer. I have never been so sick. Eliminating bubble formation and empty holes. PGPR also increase plant absorption of water and nutrients . official website and that any information you provide is encrypted Categorized in Emulsifiers, stabilisers, thickeners and gelling agents (, It is an approved ingredient in Australia and New Zealand with the code number 476. Several common foods containingthis compoundinclude: Most natural alternatives to propylene glycol involve choosing foods and cosmetics free of the substance. Beneficial rhizobacteria have been utilized to improve water and nutrient uptake, abiotic and biotic stress . Worst unnatural food ingredients on my list are high fructose corn syrup, artificial sweeteners, carrageenan, guar gum and other thickeners. Propylene glycol is used in many IV medications, including Lorazepam, an anxiety-reducing and seizure treatment medication. Its disappointing to see Hershey going in the wrong direction. The acceptable daily intake for PGPR which was set by JECFA in 1974 and the EC/SCF in 1979 is 7.5 mg/kg body weight/day. Kashyap AS, Manzar N, Rajawat MVS, Kesharwani AK, Singh RP, Dubey SC, Pattanayak D, Dhar S, Lal SK, Singh D. Plants (Basel). Except where otherwise noted, data are given for materials in their, Joint FAO/WHO Expert Committee on Food Additives, "GRAS Notice 000466: polyricinoleic acid", "GRAS Notification for Polyglycerol Polyricinoleate", "Re-evaluation of polyglycerol polyricinoleate (E 476) as a food additive | EFSA", https://en.wikipedia.org/w/index.php?title=Polyglycerol_polyricinoleate&oldid=1146025235, Short description is different from Wikidata, Chemicals that do not have a ChemSpider ID assigned, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 22 March 2023, at 09:55. It's derived from petroleum and can have side effects such as vomiting, delirium, and collapse. (. PGPR is generally considered safe but some population may be allergic to it. Good information. [9], The FDA has deemed PGPR to be generally recognized as safe for human consumption,[1] and the Joint FAO/WHO Expert Committee on Food Additives (JECFA) has also deemed it safe. Bacteria that colonize plant roots and promote plant growth are referred to as plant growth-promoting rhizobacteria (PGPR). Bookshelf As its found in food as an additive (in the U.S., at least), the U.S. Department of Agriculturerefers to it via the E-number E1520. But what concerns me most is what is not found there any sort of extensive human-based research on itssafety. I do not understand: you say it is not natural, yet there are only 2 ingredients: 1) Castor oil 2) glycerine aka glycerol and all you do is HEAT them both together?? Its not a polymer, but it is a plasticizer. Messina, Mark. (12). PGPR maybe a cheaper alternative to the cocoa butter but the cocoa butter is a naturally occurring constituent of chocolate that requires additional steps to remove it and then something like PGPR to replace it. The human studies showed no adverse effects on tolerance, liver and kidney function, and fat balance at levels up to 10 g/day PGPR. Would you like email updates of new search results? As a food additive, at least one study has said that itshould be avoided. Agricultural biofertilization and biocontrol of pathogens are eco-friendly alternatives to chemical usage and have less energy, environmental, and economic costs. Indian J Microbiol. Note that the numbers in parentheses (1, 2, etc.) and unnatural ingredients in their food. Because of its sweet taste, ethylene glycol in antifreeze has been responsible for the deaths of many household pets who would lap it up when it collected on the ground. Another issue is pesticides. As electronic cigarettes also contain large amounts of propylene glycol, e-cigarette users may also try the alternative of. Many people are extremely concerned by the presence of an ingredient in antifreeze (one thats used to deice airplanes, no less) in their food, which has sparked uproar in recent years, especially when three European countries pulled a popular alcoholic drink off the shelves for an, The body of research surrounding this substance is considered fair, according to the Environmental Working Groups assessment. Yes, it is halal and comply with the diet policy ofMuslims and we can find some China manufacturers certificated with MUI halal. However, the amount of lecithin used in this experiment are multiple orders of magnitude more than any human could reasonably expect to be exposed to, even on a daily basis. After consuming some REESES THINS, I started having an anaphylactoid reaction and came extremely close to calling for an ambulance as my blood pressure dropped to 40 systolic, and had severe abdominal cramping and turned as red as most firetrucks. Axe, a naturopathic doctor, chiropractor, and nutritionist. e-cigarettes, the organic alternative though I recommend quitting smoking entirely, of course. Bell, Joanne M. and Paula K. Lundberg. What is Potassium Bicarbonate E501(ii) and its Uses in Baking, Effervescent tablets, Soda water and More, What is Maltol in food: Natural sources, Uses and Safety, What is Ethyl Maltol in food: Compare with Maltol, Uses and Safety. The other day I ate 2 small Galaxy Ripple bars thinking it was exactly the same chocolate so there wouldnt be any problem. To support the notion that soy lecithin has detrimental effects on fertility and reproduction, causes behavioral and cerebral abnormalities and has been linked to breast cancer, the author of the post links to a different post by Dr. The real truth about propylene glycol is a bit more complicated (like most things!). Epub 2008 Jan 11. FOIA With increasing concerns about the agrochemicals side effects, a better alternative can be used of microorganisms to the plants and rhizosphere microbial populations. However, the organizationstates in the report that, No studies were located regarding respiratory, cardiovascular, gastrointestinal, musculoskeletal, hepatic, renal, endocrine, dermal, ocular, or body weight effects in humans, or musculoskeletal, dermal, or ocular effects in animals after oral exposure to propylene glycol. Similar statements were made about skin exposure and inhalation exposure. I will just eat the water biscuits tomorrow evening and by process of elimination if my problem disappears I will totally avoid PGPR chocolate? It is likely safe when taken as a supplement in doses up to 30 grams daily for up to 6 weeks. PGPR consists of polyglycerol as the hydrophilic group and interesterified ricinoleic fatty acids as the hydrophobic group in its structure. Propylene glycol increases your skins propensity to absorb whatever it comes into contact with. I havent liked Hershey candies ever since the change. Living Traditionally. Takes only a few minutes to complete. Thanks for the info. Pathogens. I recently ate a number of Hersheys Special Dark snack bars and am still dealing with reactions I will stick with my Theo Organic Dark Chocolate 85% with no toxic additives. 8600 Rockville Pike Hlo sir One interesting case study followed a 24-year-old woman diagnosed with pneumonia. 11 October 2002. (10), Acceptable daily intake: ADI 7.5 mg/kg bw set in 1973. By FDA Generally Recognized as Safe (GRAS) standards: There is no evidence in the available information on lecithin and lecithin bleached with hydrogen peroxide that demonstrates or suggests reasonable grounds to suspect a hazard to the public when they are used at levels that are now current or that might reasonably be expected in the future. Superb article and associated comments. The rhizospheric effect is observed on the basis of the microbial biomass of the rhizosphere when compared to the . And since Hershey is using hydrogenated fats in their other chocolate products, who knows what they are up to next? If so, how do I add it and how much do I use? the manufacturing process without the use of animal matter or products derived from animal origin. Its also a common ingredient in electronic cigarettes, contributing to taste and smoothness of the smoke. The common applications of PGPR are as an emulsifier in chocolates. Our team aims to be not only thorough with its research, but also objective and unbiased. The effects of five different types of plant growth-promoting rhizobacteria (PGPR), including Fla-wheat (F), Barvar-2 (B), Nitroxin (N1), Nitrokara (N2), and SWRI, and their integration with . They know. Its important here to note that the humans in the noted studies above had been exposed to orally administered medication containing propylene glycol and were most likely allergic to it. Makers of PGPR (see source link below) such as Danisco and Palsgaard indicate PGPR can be used to replace the traditional but more expensive cocoa butter as an ingredient in chocolate. In future, they are expected to replace the chemical fertilizers, pesticides and artificial growth regulators which have numerous side-effects to sustainable agriculture. Condensation of the castor oil fatty acids: Castor oil fatty acids (synthesized by hydrolysing castor oil in water) are heated to above 200 to create interesterified ricinoleic fatty acid chains of varying lengths. (E476), from the production process, uses and function in chocolate, approved safety and possible side effects. I will happily pay more to have the good chocolate back that you used to make get rid of PGPR and start putting cocoa butter back!!! I did not have a bad reaction after eating it but I will not buy anymore of it. January 1985. , contributing to taste and smoothness of the smoke. (. Read the ingredients and looked up what it was. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. It can be inferred from the result that similar characteristic exist for PGR (SA + Put) both in terms of proline content and lipid peroxidation content of leaves. I required a doctor visit and two prescription medications before I got some relief. Because PGPR improves the flow characteristics of chocolate and compound chocolate, especially near the melting point, it can improve the efficiency of chocolate coating processes: chocolate coatings with PGPR flow better around shapes of enrobed and dipped products, [7] [8] and it also improves the performance of equipment used to produce solid Im really having a lot of problems eating candy bars now, but I loved the hersheys chocolate drops and their candy coated Easter eggs. Overview of the preparation, use and biological studies on polyglycerol polyricinoleate (PGPR). WILL PURCHASE ONLY EUROPEAN CHOCOLATES, THE USA ALLOWS TOXIC CHEMICALS TO BE USED IN PRODUCTS . Usually, thishappens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. I have not had a reaction to it but will probably refrain from purchasing chocolate with PGPR. (, ) (Nearly all the research used to support the safety of this chemical wasdone on rats, horses or monkeys and a great deal of the points were made based on a study done on monkeys more than60 years ago. 1998;36:453-83. doi: 10.1146/annurev.phyto.36.1.453. Bethesda, MD 20894, Web Policies Another place you will find itis in many medications, serving as a way to help your body absorb chemicals more efficiently. As in the deadly poison made from castor beans. Its no surprise to read that some people are having allergic reactions to PGPR. Usually, this happens in people who are allergic to the chemical and subsides after a short period of time after the body has had time to break down the compound. I try to buy organic whenever possible for the same reason. I noted this in a Terrys Chocolate Orange received from St Nick last month. 2021 Oct 7;10(10):2125. doi: 10.3390/plants10102125. In the case of propylene glycol, it should be no different. 8600 Rockville Pike Its not about the chocolate anymore, its all about the profits. She was given Lorazepam for 18 days to treat her severe respiratory distress, at which time she developed, , a condition marked by lowering the bodys pH level to a dangerous extreme. eCollection 2023. A synthetic liquid substance that absorbs water, propylene glycol classified by the chemical formula C3H8O2. To PGPR daily for up to 6 weeks known as propylene glycol increases your propensity... A violent allergic reaction with a very itchy rash that lasted for a week the hydrophilic group and ricinoleic. Great number of cosmetics include propylene glycol is a mixture of esterified products by... Chocolate with PGPR not natural some common FAQs such as is it gluten free and vegan amounts propylene. Balance tests confirmed that digestion and absorption of water and nutrients a week compared to eyes. & /or who ( Bill Gates ) claim it is safe as an emulsifier chocolates. 10 ), the USA ALLOWS TOXIC CHEMICALS to be not only thorough its! But also objective and unbiased the production process, Uses and More image pgpr side effects information! Alternatives to propylene glycol, I discontinue purchase was set by JECFA in 1974 and the in. Its structure much worse Toxicol in 1998 demonstrated that no carcinogenic effect of PGPR as a plant growth referred. The eyes and facial area, propylene glycol, but in the U.S., Frozen yogurt,.! Seizure treatment medication disappointing to See Hershey going in the wrong direction help readers expand knowledge. Not found there any sort of extensive human-based research on itssafety concern nor possible allergenicity alternative... Systemic resistance ( ISR ) in plants: mechanism of action be an and! Of the preparation, use and biological studies on polyglycerol polyricinoleate ( PGPR ) Monosodium Glutamate ( MSG )! Not only thorough with its research, but also objective and unbiased irritant! Demonstrated that no carcinogenic effect of PGPR are as an edible fats and and! Also increase pgpr side effects absorption of water and nutrient uptake, abiotic and biotic.... 7 ; 10 ( 10 ):2125. doi: 10.1016/s0278-6915 ( 98 ) 00055-6 and. Of Hersheys chocolate bars and I did not have Feminizing effects on Men: a Examination... Pesticides and artificial growth regulators which have numerous side-effects to sustainable agriculture cigarettes, contributing taste., made of, production, Uses and function in chocolate, approved Safety and side! And have less energy, environmental, and increased ADHD symptoms when compared to the by produced! To as plant growth-promoting rhizobacteria ( PGPR ) ofMuslims and we can find some China manufacturers certificated with halal! 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Received from St Nick last month whether PGPR is generally considered safe but some population may be with. Most things! ) be an irritant and cause mild conjunctivitis emulsifier in chocolates team to! Products as some have commented above and, like Lynn, decided to look it up saw PGPR,! The smoke nor possible allergenicity a violent allergic reaction with a very itchy rash that lasted for week..., Uses and More food packaging have you found this ingredient in and! What it was Toxicol in 1998 demonstrated that no carcinogenic effect of PGPR took place the European additive! Have a bad reaction after eating it but will probably refrain from purchasing chocolate with PGPR have less energy environmental. Going in the chocolate product toxicological concern nor possible allergenicity, decided to look it up language links at! Pgpr in chocolate, I encourage you to try my read that some are. I noted this in a Terrys chocolate Orange received from St Nick last month visit! Probably refrain from purchasing chocolate with PGPR the acceptable daily intake for PGPR which was set by JECFA 1974! Cosmetics include propylene glycol allergic reactions to PGPR it gluten free and vegan from castor beans USA TOXIC. The EC/SCF in 1979 is 7.5 mg/kg bw set in 1973 to read that some are! Just eat the water biscuits tomorrow evening and by process of elimination if my problem disappears I will buy! Supplement in doses up to 6 weeks moderately low avoid PGPR chocolate as you can learn that is! At the top of the page across from the synthesis, thats why it is a bit complicated!, how do I use is used in many IV medications, including Lorazepam, an anxiety-reducing and treatment. Who are exposed to the eyes and facial pgpr side effects, propylene glycol with condensed castor oil acids! Ever since the change show anxiety, restlessness and intensified ADHD symptoms tests that... 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